Claudio Bordignon Selected Research

mouse CNGRC fusion protein tumor Necrosis Factor-alpha

10/2015

The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms.

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Claudio Bordignon Research Topics

Disease

37	Neoplasms (Cancer) 11/2020 - 01/2002
14	Leukemia 01/2018 - 11/2002
9	Graft vs Host Disease (Graft-Versus-Host Disease) 02/2013 - 01/2002
8	Hematologic Neoplasms (Hematological Malignancy) 01/2015 - 01/2002
6	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2009 - 05/2002
4	Lymphoma (Lymphomas) 11/2020 - 04/2008
4	Multiple Myeloma 01/2020 - 07/2007
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 01/2006
4	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 08/2013 - 04/2004
4	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2009 - 06/2002
3	Neoplasm Metastasis (Metastasis) 01/2020 - 12/2011
3	Infections 12/2009 - 03/2004
2	Carcinogenesis 01/2020 - 10/2016
2	Inflammation (Inflammations) 01/2018 - 01/2010
2	Inborn Genetic Diseases (Disease, Hereditary) 12/2017 - 06/2006
2	Breast Neoplasms (Breast Cancer) 03/2015 - 06/2002
2	Melanoma (Melanoma, Malignant) 06/2013 - 02/2009
2	Necrosis 10/2010 - 01/2010
2	Chills 05/2010 - 01/2010
2	Hematologic Diseases (Blood Diseases) 03/2010 - 06/2006
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2008 - 06/2002
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2020
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019
1	Fever (Fevers) 01/2018
1	Cytokine Release Syndrome 01/2018
1	Lewis Lung Carcinoma 11/2016
1	Hypoxia (Hypoxemia) 10/2016
1	Primitive Neuroectodermal Tumors (PNET) 10/2016
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 10/2016
1	Experimental Melanoma 03/2015
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 08/2013

Drug/Important Bio-Agent (IBA)

8	human CNGRC fusion protein tumor necrosis factor-alphaIBA 11/2020 - 01/2010
8	AntigensIBA 01/2020 - 03/2006
8	Peptides (Polypeptides)IBA 01/2019 - 09/2008
7	EnzymesIBA 10/2016 - 05/2002
7	Thymidine KinaseIBA 06/2013 - 11/2002
5	Adenosine DeaminaseIBA 01/2009 - 06/2002
4	Protein Isoforms (Isoforms)IBA 01/2020 - 01/2010
4	Pharmaceutical PreparationsIBA 01/2019 - 01/2010
4	CytokinesIBA 01/2019 - 12/2004
4	CD13 Antigens (Alanine Aminopeptidase)IBA 04/2011 - 01/2010
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2020 - 01/2002
3	Chimeric Antigen ReceptorsIBA 01/2020 - 01/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 09/2008
3	OxysterolsIBA 11/2016 - 08/2013
3	CholesterolIBA 11/2016 - 01/2010
3	Cerebroside-Sulfatase (Arylsulfatase A)IBA 08/2013 - 05/2005
3	Neoplasm Antigens (Tumor Antigens)IBA 06/2013 - 10/2007
3	LigandsIBA 01/2010 - 09/2008
3	purineIBA 01/2009 - 11/2006
3	Proteins (Proteins, Gene)FDA Link 09/2008 - 10/2007
2	Methotrexate (Mexate)FDA LinkGeneric 01/2019 - 12/2009
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019 - 01/2018
2	Interleukin-1 (Interleukin 1)IBA 01/2019 - 01/2018
2	AcidsIBA 01/2019 - 11/2016
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2019 - 01/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2016 - 03/2015
2	Liver X ReceptorsIBA 08/2013 - 01/2010
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2012 - 07/2003
2	asparagine-glycine-arginineIBA 04/2011 - 05/2010
2	Biomarkers (Surrogate Marker)IBA 12/2009 - 01/2006
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 12/2009 - 06/2002
2	Interleukin-7 (Interleukin 7)IBA 01/2009 - 12/2004
2	fludarabineIBA 06/2002 - 01/2002
2	Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric 06/2002 - 01/2002
1	Vincristine (Oncovin)FDA LinkGeneric 11/2020
1	Prednisone (Sone)FDA LinkGeneric 11/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2020
1	Rituximab (Mabthera)FDA Link 11/2020
1	CD44v6 antigenIBA 01/2020
1	Cytostatic AgentsIBA 01/2019
1	AlarminsIBA 01/2019
1	InflammasomesIBA 01/2019
1	Thymic Stromal LymphopoietinIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2018
1	tocilizumab (atlizumab)FDA Link 01/2018
1	Immunomodulating AgentsIBA 01/2018
1	Monoclonal AntibodiesIBA 01/2018
1	Zoledronic Acid (Zometa)FDA Link 11/2016
1	Terpenes (Terpenoids)IBA 11/2016
1	Cholesterol 24-Hydroxylase (CYP46A1)IBA 10/2016
1	24-hydroxycholesterolIBA 10/2016
1	mouse CNGRC fusion protein tumor Necrosis Factor-alphaIBA 10/2015
1	Interleukin-22 (IL-22)IBA 05/2015
1	Angiogenesis InhibitorsIBA 03/2015
1	Ganciclovir (Cytovene)FDA LinkGeneric 02/2013
1	ProdrugsIBA 02/2013
1	HLA Antigens (Human Leukocyte Antigens)IBA 02/2013
1	N-end cysteine peptide tumor-homing peptideIBA 01/2013

Therapy/Procedure

13	Therapeutics 01/2020 - 12/2004
10	Hematopoietic Stem Cell Transplantation 01/2018 - 07/2003
8	Transplantation 01/2018 - 01/2002
5	Stem Cell Transplantation 07/2009 - 06/2002
4	Immunotherapy 01/2018 - 03/2010
3	Drug Therapy (Chemotherapy) 01/2019 - 04/2008
3	Cell Transplantation 06/2011 - 11/2002
2	Enzyme Replacement Therapy 11/2006 - 05/2005
2	Homologous Transplantation 06/2002 - 01/2002
1	Induction Chemotherapy 01/2018
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2015